MH@H Depression

Ketamine for treatment-resistant depression

Ketamine for Treatment-Resistant Depression

Ketamine is a relatively new option for managing treatment-resistant depression that has a different mechanism of action from other antidepressant medications. Ketamine itself isn’t new, though; it’s a dissociative anaesthetic that’s also known by its club drug name Special K. Over the last 10-15 years, multiple research trials have shown that it has an antidepressant […]

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Evidence-based treatment of mental illness

Do Antidepressants Work Better Than Placebo?

Do antidepressants work? There’s a lot of stigma around psychiatric medications, and plenty of people would argue that no, antidepressants don’t work. There are also people, that argue that medication is life-saving. Those are personal experiences, but what does the research have to say? A recent paper published in the Lancet, and reported on in

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I'm Actually Getting Stupider: Cognitive symptoms of depression

The THINC-it Test for Cognitive Symptoms of Depression

Despite what the title might suggest, this post isn’t about me being self-critical. I’ve been struggling for months with cognitive symptoms of depression, and on a daily basis I notice that it impairs my overall functioning. But it’s not something I’ve ever had much of an objective sense of, until I tried the THINC-it test.

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Feeling Like a Stranger in My Own Family

I never would have thought that I would feel like a stranger in my own family. Depression changed everything, though. The present story I spent Christmas with my family this year. It was a small gathering – just my parents, my brother, his fiancee, and me. Except it didn’t feel small; it seemed like there

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Mashed potato brains: Dealing with cognitive symptoms of depression

Mashed Potato Brains in Depression

I have always found the cognitive symptoms of depression to be among the most disruptive to my overall functioning.  When I’m really unwell it feels like I can’t think my way out of a paper bag.  I tend to describe the effect on my thinking as “mashed potato brains”.

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