Treatment-resistant depression: image of pills falling into a bowl
Depression

Treatment-Resistant Depression: When What’s Supposed to Work Doesn’t

Wouldn't it be nice if the treatment of depression was simple?  Unfortunately, there's nothing simple about depression treatment in the real world.  Treatment-resistant depression (TRD) refers to illness that hasn't respond to trials of adequate duration and dosage of at least two antidepressants.  The STAR*D research study found that only about 1/3 of people get… Continue reading Treatment-Resistant Depression: When What’s Supposed to Work Doesn’t

Ketamine for depression: how it works, side effects, and how it's used
Depression

Ketamine for Treatment-Resistant Depression

I love Canada, but sometimes we're a little behind.  Drug approval by Health Canada is slower than in the US, and fewer clinical trials are done here.  I'd be really interested in trying out ketamine, but it doesn't have Health Canada approval for use in depression, there are no clinical trials in my neck of… Continue reading Ketamine for Treatment-Resistant Depression